Next Generation Sequencing
Next-Generation sequencing (NGS) performs massively parallel sequencing of genomes, allowing for the analysis of a significant number of genomic targets with a single test. Critically, NGS allows for the detection of aberrations that may only be present at very low levels, but which may have important clinical relevance for the patient’s diagnosis and prognosis.
DNA-FISH Probes
Fluorescence in situ hybridization (FISH) is used to detect chromosomal aberrations such as DNA copy number changes (gain/loss) and rearrangements (translocation/break apart). FISH is a method of choice for diagnosis, prognosis, and treatment response prediction for a number of hematological and solid tumor cancers
CGH Microarrays
Microarray based technology assesses a large number of genetic alterations in a single experiment. One application of this technology, known as array-CGH, is utilized to evaluate DNA copy number changes (gains/losses) observed frequently in tumor genomes. We have designed disease-specific, targeted microarrays for diagnostic and prognostic purposes in a variety of cancers.
Pharmacogenomic Testing
Pharmacogenomic testing is becoming increasingly central to the field of personalized medicine. Pharmacogenomic testing assesses biomarkers associated with drug metabolism and is used to help reduce the incidence of adverse drug reactions and predict how an individual patient will respond to a given medication. Pharmacogenomics can help ensure that patients get the right medication and the right dose.
Liquid Biopsy
Blood Test for Cancer Detection & Treatment Planning
CIRCULATING TUMOR CELL – Detection Test
Breast Cancer – Colon Cancer – Prostate Cancer
SINGLE TEST – BEFORE CHEMOTHERAPY
CIRCULATING TUMOR CELL – Breast, Colon & Prostate
INCLUDES 2 TESTS
PRE- CHEMOTHERAPY AND
AFTER 1ST CYCLE OF CHEMOTHERAPY –
CIRCULATING TUMOR CELL – Breast, Colon & Prostate
INCLUDES 3 TESTS
PRE-CHEMOTHERAPY
AFTER 1ST CYCLE OF CHEMOTHERAPY &
AFTER 1 YEAR OF CHEMOTHERAPY COMPLETION
Liquid Biopsy – Lung Cancer
Cell free DNA – EGFR Mutation Detection
Liquid Biopsy Colon Cancer
Cell free DNA (BRAF, NRAS, KRAS)
Liquid Biopsy – Colon Cancer
Cell free DNA – KRAS
Liquid Biopsy – Colon Cancer
Cell free DNA – BRAF
Liquid Biopsy – Colon Cancer
Cell free DNA – NRAS
Next Generation Sequencing
Clinical Grade Test to Detect Drugable Cancer Mutations
Next Generation Cancer Hot Spot Panel – 50 Genes
(DNA – RNA – Pharmacogenomics)
BRCA1 & BRCA2
Breast and Ovarian Cancer
NGS-Lung Cancer Mutation & Fusion Panel
23 genes and 6 fusion transcripts (FDA IVD Approved)
NGS – Lung Focus Panel
(52 genes, 26 copy Numbers)
Lung Cancer Tests
NGS – Liquid Biopsy – Molecular Tests
NGS – 50 Gene Cancer Hot Spot Panel
(DNA – RNA – Pharmacogenomics)
Lung Cancer Mutation & Fusion Panel
23 genes and 6 fusion transcripts (FDA IVD Approved)
NGS – Lung Focus Panel
(52 genes, 26 copy Numbers)
Liquid Biopsy – Cell Free DNA
Droplet Digital PCR (EGFR L858R, E746_A750del,& T790M)
Liquid Biopsy – CIRCULATING TUMOR CELL
Detection & Enumeration – PFS/OS
PREDICITIVE LUNG CANCER PANEL –
EGFR BY ARMS PCR
ALK BY IHC
ROS1 BY FISH
MET BY FISH
EGFR mutation analysis for Exon 18 to 21
EGFR by RT PCR and ROS translocation by FISH
FISH-B.A. Test for EML-ALK fusion
Lung Multi-Gene
EGFR BY RT PCR
ROS1 translocation by FISH &
ALK by IHC
ROS1 BY FISH
ROS1 & MET BY FISH
CMET amplification by FISH and PDL1 by IHC
FISH-B.A. Test for EML-ALK fusion
BREAK APART FISH FOR – RET
Breast Cancer Tests
NGS – Liquid Biopsy – Molecular Tests
NGS – 50 Gene Cancer Hot Spot Panel
(DNA – RNA – Pharmacogenomics)
Liquid Biopsy – CIRCULATING TUMOR CELL
Detection & Enumeration – PFS/OS
BRCA1 & BRCA2 by Next Gen Sequencing
BRCA1 & BRCA2 by Testing By MLPA
HER2 exon 20 and BRAF mutation analysis
FISH for HER2 Neu copy number gain
HER2 amplification and RET rearrangement – FISH
Colon Cancer Tests
NGS – Liquid Biopsy – Molecular Tests
NGS – 50 Gene Cancer Hot Spot Panel
(DNA – RNA – Pharmacogenomics)
Liquid Biopsy – CIRCULATING TUMOR CELL
Detection & Enumeration – PFS/OS
Liquid Biopsy – Colon Cancer
Cell free DNA (BRAF, NRAS, KRAS)
Liquid Biopsy – Colon Cancer
Cell free DNA (BRAF)
Liquid Biopsy – Colon Cancer
Cell free DNA (NRAS)
Liquid Biopsy – Colon Cancer
Cell free DNA (KRAS)
Colon Molecular profiling of KRAS & NRAS
Extended Molecular Profiling – KRAS, NRAS and BRAF
KRAS mutation analysis (codon 12,13,61)
NRAS mutation analysis (codon 12,13,61)
Prostate Cancer Tests
NGS – Liquid Biopsy – Molecular Tests
NGS – 50 Gene Cancer Hot Spot Panel
(DNA – RNA – Pharmacogenomics)
Liquid Biopsy – CIRCULATING TUMOR CELL
Detection & Enumeration – PFS/OS
Tests for Sarcoma
NGS – Liquid Biopsy – Molecular Tests
NGS – 50 Gene Cancer Hot Spot Panel
(DNA – RNA – Pharmacogenomics)
FISH-B.A. Test for Ewings Sarcoma/Synovial Sarcoma
FISH-B.A. Test for EWSR1(Chr.22) (Ewings Sarcoma/
FISH-B.A. Test for SS18 (Chr. 18) (Synovial Sarcom
Tests for Melanoma
NGS – Liquid Biopsy – Molecular Tests
NGS – 50 Gene Cancer Hot Spot Panel
(DNA – RNA – Pharmacogenomics)
Liquid Biopsy – Cell Free DNA – BRAF
c-KIT Mutation for Melanoma
BRAF & c-KIT MELONAMA
c-KIT Mutation & PDGFRA Mutation for GIST
Brain Tumor Tests – Glioblastoma
NGS – Liquid Biopsy – Molecular Tests
NGS – 50 Gene Cancer Hot Spot Panel
(DNA – RNA – Pharmacogenomics)
FISH for 1p36/1q25 and 19q13/19p13 codeletion
MGMT MS-PCR
Acute Lymphocytic Leukemia
ALL Translocation Panel
[t( 1;19) ,t(12 ;21), t (4;11),t(9; 22)]
Acute Myeloid Leukemia
AML Comboquest
NPM1 mutation analysis
FLT3 mutation analysis
CEBPA mutation analysis
AML Prognostic (NPM1 mutation, FLT3 mutation)
AML Translocation Extended Panel
[t(8;21),t(15;17),inv16,FLT3,NPM1]
AML Translocation Panel
[t(8;21),t(15;17),inv16]
PML-RARa t(15;17)/aml-eto T(8;21)/inv16 QUALITATIV
FLT3 muations (ITD & D835) Restriction Digestion
Chronic Myeloid Leukemia
Qualitative PCR for JAK2 V617F Exon 14 mutation de
Quantitative PCR t(9;22) BCR/ABL
BCR-ABL QUALITATIVE BY RT-PCR
BCR-ABL BY FISH
IRMA – BCR/ABL Kinase Domain Mutation analysis
(Molecular Analysis of Acquired Resistance to Imatinib)
Chronic Lymphoid Leukemia
FISH FOR CLL
Lymphoma’s
Bcl2, Bcl6 & Cmyc Translocations by FISH
C-myc by FISH
BCL 2 by FISH
BCL 6 by FISH
Bcl2, Bcl6 & Cmyc Translocations by FISH
Hereditary Disease – Genetic Tests
To help you understand your risk of developing a disease
myGenome
Whole Genome Sequencing
myCarrier
Saliva-based screening of prospective or currently pregnant parents for carrier status of inherited and rare conditions such as cystic fibrosis, dystrophies, and other debilitating genetic conditions.
myNewborn
Comprehensive screening of newborns for early childhood diseases, primarily monogenic, Mendelian disorders for which genetic screening by DNA sequencing is ideal and for which medical preventive, surveillance, or treatment interventions are possible.
myPrenatal
Maternal Blood bases non invasive screening test that predicts the presence of Down Syndrome (T21), Edwards Syndrome (T18) and Patau Syndrome (T13).
DUMMY TEXT